Photodynamic Therapy for acne uses a photosensitizing agent called Levulan
(aminolevulinic acid, or ALA), which is selectively absorbed by acne-causing sebaceous
glands and Cutibacterium acnes (formerly Propionibacterium acnes) bacteria. When activated by blue light, Levulan generates
reactive oxygen that reduces bacterial load and sebaceous gland activity.
Unlike systemic medications, PDT acts precisely where the problem is — with minimal
impact on surrounding healthy tissue. Its precision is what allows for such targeted,
effective results with a favorable side effect profile.
Dr. Zaks often combines PDT with laser treatment — such as the Vbeam pulsed-dye laser —
to simultaneously address inflammation, redness, and early scarring. This combination
protocol delivers results that are often significant and long-lasting for many patients,
particularly those with cystic or treatment-resistant acne.
"Photodynamic Therapy has been very effective in helping to control cystic acne. Since acne cysts are
responsible for acne scarring, it has become a key option for both immediate acne
management and prevention of post-acne scars."
— Dr. Boris Zaks, MD | as featured in Glamour Magazine